For The Better

Precision medicine is an approach that considers patients’ individual differences in genes, environment, and lifestyle to personalize medical treatments. In the case of cancer, precision medicine involves the identification of specific molecular traits or mutations that drive tumor growth. This information is then used to tailor the treatment of each individual patient. “Every tumor is …

Over the last decade, chimeric antigen receptor (CAR) T-cell therapies have attracted growing interest for their potential to treat a wide range of cancers. To date, six CAR T-cell therapies have been approved by the FDA, all for the treatment of hematological malignancies such as leukemia and lymphoma. In contrast to the success of CAR …

Anyone looking for reasons for the explosion of interest in biofuels need look no further than the adverse effects of our dependence on fossil fuels. Climate change, the increase of pollutants in our air and water, the high cost of conventional fuels, and the desire to reduce dependence on foreign energy sources are just some …

The push to reduce global warming has resulted in nearly 70 countries declaring carbon net-zero targets, with an aim to reduce 76% of global emissions. Some of the largest carbon generators – the European Union, China, and the United States among them – have joined net-zero initiatives, with the US announcing the ambitious goal of …

Sustainability is on the minds of business leaders and consumers more than ever. And growing numbers of organizations are adding sustainable policies and practices to their solutions and services, minimizing waste and environmental impact. They’re reducing carbon emissions, using more renewable energies, and increasing efforts to move toward circular economies. There’s no shortage of approaches …

In recent years, interest in human three-dimensional (3D) organ-like microtissues called organoids has skyrocketed, with citations increasing exponentially in the scientific literature over the past decade. Organoids are structurally and cellularly complex, with functions which mimic their human organ counterparts. These characteristics give them distinct advantages over traditional two-dimensional (2D) monolayer cell systems, which do …

The ability to knockout genes using the CRISPR-Cas9 system has revolutionized the way that researchers study gene function, providing previously unobtainable insights into biological pathways. CRISPR knockout experiments are often performed in animal models or immortalized human cell lines to study gene function and explore the effects of gene edits on the phenotype or behavior …

In the years since hybridoma technology was invented, over 100 mAbs have entered the clinic and this class of drugs represents one of the fastest-growing areas of research and development. However, the production of hybridomas is ridden with potential bottlenecks and involves several steps, including the inoculation of mice with specific antigens, isolation of antibody-secreting …

The need for faster and more efficient analysis of larger and more complex samples has driven the development of advanced instruments in the lab, leading to the creation of improved instruments capable of handling increasing demands for productivity and accuracy. For the identification and quantification of compounds, liquid chromatography (LC) coupled with mass spectrometry (MS) …

High-performance liquid chromatography (HPLC) has become a widely used analytical technique in today’s laboratories – a go-to technology for separation, identification, and quantification of components in the most complex organic samples for a wide range of applications, from food safety to pharma QA/QC. Based on the groundbreaking chromatographic work of J.P. Martin and R.L. Millington …