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Food Viscosity Testing Above the Boiling Point

Many modern food processing techniques require temperatures at or above 100° C, but few rheological devices offer analysis at that temperature. Modern food processing techniques such as pasteurization and sterilization require high temperatures beyond the boiling point of water. Understanding how a food product will behave above 100° C matters when determining best methods and …

Newborn Screening Virtual Summit: 45+ Thought Leaders. 24-hours of Learning. One Amazing Location.

Log-in and Learn on December 8.  (Free: pre-register here) Prominent biochemist Linus Pauling once said: “If you want to have good ideas, you must have many ideas.” One of the best ways to propagate new ideas, particularly in science, is discussion with your colleagues. We typically use exhibitions and congresses for these discussions and display …

Expertise, Expectations & Excipients in Medicine

Consumers expect that the medicines they need are guaranteed to be effective and safe. This means that throughout the entire manufacturing process, as well as during research and development, all standards of quality are being met or exceeded. While most people are probably unaware of all the ingredients that make up their medicine, pharmaceutical manufacturers …

COVID-19’s Influence on Neurological Symptoms

Research of neurological symptoms associated with SARS-CoV-2 presents an opportunity to further understand COVID-19 molecular functioning as well as its implications in the clinic. Symptoms of COVID-19 typically affect the respiratory system, including fever, dry cough, and shortness of breath. On the other hand, observations of secondary complex symptoms affecting the central nervous system may …

Risks and Rules of Impurities in Drug Substance and Drug Product

Impurities in drug substances and drug products provide no therapeutic benefit. Heavy metals – arsenic, cadmium, mercury, and lead, for example – are not generally useful in pharmaceutical production… but are still present as impurities. Controlling these substances is not only imperative to the health of patients, but also to the integrity of drug manufacturers. …

Finding Harmony With ICH, Regulatory Authorities and Pharmacopoeias

While harmonization efforts and the leadership of the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) and World Health Organization (WHO) have proven helpful in minimizing the prior variance and complexity in the drug development pathway for GMP-regulated labs, their interactions with individual pharmacopoeial monographs, as well as regulatory agencies, …

Removing the Headache from Dissolution Testing

Quality and Compliance – Where You Need Them Most Pharmaceutical labs consider dissolution testing to be one of the critical steps in the drug development process. And it makes its impact at almost every step of the journey, from early product development to late-stage quality control. Dissolution testing helps labs control key variables in the …

Identifying Antivirals and Vaccines with the Power of High Content Screening

Researchers worldwide are working around the clock to develop effective drugs and vaccines for the SARS-CoV-2 virus. Their efforts are focused on three key approaches: Repurposing of existing drugs Development of new therapeutics Development of vaccines High content screening (HCS), with its wide range of applications, is an important part of each of these strategies. …

Studies in Humanized Mice and Convalescent Humans Yield a SARS-CoV-2 Antibody Cocktail

Antibody therapies have become an important tool in treating diverse conditions such as autoimmune diseases, cardiovascular diseases, allergic conditions, infectious diseases, and cancers. Proven methods for developing such antibody therapies include using mice with genetically humanized immune systems and human B cells to produce fully human antibodies. These approaches have recently been used to develop …

Watch Your Batch: Tips for a Smooth Drug Product Release

When it comes to your batch release – whether it’s a drug’s introduction to the market or the return of an existing product – a seamless rollout can save your reputation and minimize overhead costs. Ensuring that you follow standard procedures and protocols is essential in all stages of the process to guarantee success. We’ve …

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