Revvity blog

Professionals who need to preform scRNAseq on samples collected from remote locations, need a solution that stabilizes the molecular footprint of a sample and allows it to be processed in a centralized lab which could be located far away from the collection site. In this video you can meet the researchers studying bone loss during …

Decades of research and technological advancements are enabling scientists to more fully understand how tumors proliferate, metastasize, and evolve. For example, researchers can now characterize tumors through comprehensive profiling to identify and develop targeted therapeutic interventions for each patient. Patient-derived xenograft (PDX) models are rapidly taking the place of traditional cell line approaches to better …

As next generation sequencing (NGS) laboratories evaluate new automated sample preparation solutions, focusing on vendors who have vendor-qualified automated library protocols can play a key role in meeting their objectives. A fully vendor-qualified NGS library means the automation supplier has sent their final DNA/RNA libraries to the NGS kit provider, who sequences the libraries and …

Recent developments and novel strategies such as immunotherapies and targeted therapies have made significant advancements in cancer treatments. Long-term benefits have been demonstrated using these approaches, leading to multiple approvals from regulatory bodies. Sadly, only some treated patients develop an objective tumor response with long-term survival benefits. On top of that, the systemic delivery of …

From Bench to Sequencing in Days With the cost to sequence genomes declining dramatically, researchers are applying next generation sequencing (NGS) to new discoveries and clinical research at a rapidly expanding rate. These applications are driving new sample preparation workflows that prepare the DNA/RNA libraries prior to sequencing. This growing appetite for new kits plus …

Increasingly, we are realizing that every tumor is different, meaning that a one-size-fits-all approach to cancer treatment will be ineffective. Multiple techniques are needed to unpick the factors underlying tumor heterogeneity and to improve treatment efficacy. One notable technique is the utility of liquid biopsies to provide real-time insights into tumor evolution and treatment response. …

In the early 1970s, Professor Solomon Snyder and colleagues reported a technique that enabled the identification of opiate receptors in the brain.1 This was the first discovery of its kind, providing direct evidence for drug receptors as molecular entities. Using radioactive ligand binding methods, Dr. Snyder’s team found that the receptors were highly concentrated in …

The emergence of bispecific antibodies has been heralded as the fourth wave of biopharmaceutical innovation, providing opportunities to target two different antigens with a single therapeutic. For example, some bispecific antibodies can bind different antigens expressed on two different cell types, bringing those cells together as a more effective treatment for complex diseases. There are …

Cancer research has witnessed remarkable advancements in recent years, enabling scientists to understand many of the intricacies underlying this complex disease. One such breakthrough technology is fluorescence in vivo imaging, which utilizes fluorescent probes to detect specific oncological biomarkers and protease activity to drive the development of cancer therapies. By enabling noninvasive assessment of in …

Tuberculosis (TB) is a potentially lethal bacterial infection that spreads in the air from one person to another. Last year, the World Health Organization (WHO) reported that the number of people infected with Mycobacterium tuberculosis (Mtb), including drug-resistant strains, had risen globally for the first time in almost 20 years. The disease killed over 1.6 …