Learn why Covaris’ Adaptive Focused Acoustics (AFA) Technology for Shearing DNA Outperforms Enzymatic Fragmentation in Next Generation Sequencing Workflows. Enzyme-based methods can be unpredictable and biased, while AFA delivers consistent, reliable mechanical shearing across all sample types. The AFA enabled workflow helps Genomic research labs achieve robust, reliable, and reproducible sequencing data. DNA fragmentation is …

Organoids are an extremely valuable tool for in vitro disease modeling and hold great promise in cancer and stem cell research as well as drug discovery and screening. Intelligent organoid workflows harness advances in automation, genetic engineering, and stem cell technologies to develop sophisticated models for studying development and disease. One key advantage of organoids …

In recent years, a discernable shift has taken place in the development of cancer therapeutics, marked by a growing emphasis on innovative drug delivery strategies. The focus has been on tailoring these strategies to enhance the precision of therapeutic targeting to tumor sites. Despite the undeniable success of conventional cancer treatment methods, they have several …

Precision medicine has significant potential, but the complexity of cancer has limited its success Advances in genomic sequencing and the massive expansion in treatment options over the past two decades are changing our approach to cancer treatment. Whereas older therapeutic strategies relied on non-cancer-specific mechanisms of action, molecular profiling has supported the rise of targeted …

Immunotherapy offers new hope for cancer patients by utilizing the body’s immune system to prevent, control, and eliminate cancer cells. This transformative strategy encompasses various techniques, such as chimeric antigen receptor (CAR) T-cell therapy, immune checkpoint inhibitors (ICIs), monoclonal antibodies, and adoptive cell transfer. While CAR T-cell therapy has shown remarkable success in treating hematological …

Integral to many research and testing facilities are the high-content screening (HCS) technologies that continue to evolve alongside imaging and analysis systems. HCS platforms serve a multitude of purposes, from screening the effects of potential drug compounds on cellular processes to facilitating the study of complex biological pathways. Imaging experiments can yield valuable insights into …